Tulane Microbiologist Dr. Michael Schurr Joins Palm Beach Narcissism Diet
| Esteemed Tulane University
Microbiology Professor Dr. Michael Schurr has joined the Palm Beach
Narcissism Diet. Congrats and welcome aboard Dr. Schurr! Now you can watch the New Orleans professor shrink alongside the top Tampa news anchor, Al Ruechel, and sport psychologist John Murray. Follow Dr. Schurr's weekly progress from the links at: http://www.PalmBeachNarcissismDiet.com. I asked Dr. Schurr to provide me his brief biography, but you know those accomplished professors ... he provided his full CV ... a very healthy and conspicuos form of narcissism indeed ... and totally consistent with the Palm Beach Narcissism diet. He also sent in a before photo that will be posted soon. Dr. Schurr gets it!! So, without hesitation, I include below the academeic CV of Dr. Michael John Schurr at Tulane University! CURRICULUM VITAE NAME: Michael John Schurr tel: 504-988-4607 fax: 504-588-5144 e-mail: mschurr@tulane.edu Date and place of birth:. Madison, Wisconsin. Marital status: Married to Jill R. Schurr Education: 1992 Ph.D. in Molecular Biology. University of North Texas, Denton, Texas. (Gerard A. O’Donovan, advisor). 1983 B.S. in Biological Sciences. Loyola University of New Orleans, Louisiana. Academic positions held: 2004-date Associate Professor of Microbiology and Immunology. Tulane University School of Medicine at New Orleans, Louisiana. 70112. 1998-2004 Assistant Professor of Microbiology and Immunology. Tulane University School of Medicine at New Orleans, Louisiana. 70112. 1996-1998 Assistant Research Scientist of Microbiology and Immunology. University of Michigan Medical School, Ann Arbor, Michigan 1992-1996 Post-doctoral (Vojo P. Deretic, sponsor). University of Texas Health Sciences Center at San Antonio, Texas. Research interests: Investigations at the molecular level of Pseudomonas aeruginosa pathogenic mechanisms. Host-pathogen interaction modeling of Pseudomonas aeruginosa and lung epithelial cells. Key words: Bacterial pathogenesis, transcriptional regulation, molecular biology, Pseudomonas aeruginosa, epithelial lung cell modeling, immunology. Research Support: Cystic Fibrosis Foundation Postdoctoral fellowship. “Role of AlgP in P. aeruginosa pathogenesis”. Funded 4/1/93-3/30/96. Direct costs for the entire project: $102, 000. Postdoctoral fellowship. Cystic Fibrosis Foundation. “Mucoid regulation and AlgU in P. aeruginosa” (SCHURR95IO). Funded 7/1/96-6/30/98. Direct costs for the entire project: $68, 800. Principal Investigator. Cystic Fibrosis Foundation. “P. aeruginosa AlgR Regulon of Virulence Determinants” (SCHURR95ZO). Funded 6/1/97-6/30/99. Direct costs for the entire project: $100, 000. Principal Investigator. LEQSF-Board of Regents of the State of Louisiana. “Pseudomonas aeruginosa Virulence Factors regulated by AlgR” (LEQSF 1999-02-RD-A-42). Funded 6/1/99-5/30/02. Direct costs for the entire project: $98, 874. Principal Investigator. Louisiana State Health Excellence Fund- Board of Regents of the State of Louisiana. “Center for Lung Biology and Immunotherapy” (HEF (2000-05)-06). Funded 6/00 – 5/05. Direct costs for the entire project: $6, 757, 308. (Shellito-PI). Investigator.
Enhancement Grant-Board of Regents of the State of Louisiana.
”Microbial Pathogenesis Imaging Center” (LEQSF 2001-02-ENH-TR-69).
Funded 6/1/01-5/30/02. Direct costs
for the entire project: $117, 000. Principal Investigator. Enhancement grant-Board of Regents of the State of Louisiana. "Software Enhancement of the Tulane University Imaging Centers" (LEQSF 2004-05-ENH-TR-79) Funded 6/1/04-6/30/05. Direct costs for entire project: $50,000. Principal Investigator.
National Institute of Allergy and Infectious Diseases. “ Title”, (R21 AI63034-01) Funded 3/1/05-2/28/07, Direct Costs for entire project: $50,000, Co-Investigator. (Sauer-PI), Investigator.
Teaching: 2004 Co-course director of Graduate course: “Mechanisms of Bacterial Pathogenesis” (MIIM 704). Includes development of lecture handouts and intramural course materials. 11 lectures. Lecture topics include: (1) Recombinant DNA and genomics; (2) Transduction; (3) Recombination; (4) Bioenergetics; (5) Regulation of metabolic pathways; (6) Gram negative cell wall synthesis; (7) Protein export and secretion; (8) Adhesins; (9) Capsules; (10) Regulation of virulence factors: two-component transcriptional regulators; (11) Quorum Sensing and Biofilms. Tulane University Health Sciences Center, New Orleans, LA.
1999-present 10 lectures (1999-2000), 8 lectures (2001-2003), 6
lectures (2004) in T2 Medical Microbiology course. Lecture topics
include: (1) history of microbiology; (2) bacterial growth and
physiology; (3) microbial cell structure; (4) microbial metabolism; (5)
microbial genetics I; (6) microbial genetics II; (7) microbial genetics
III; (8) Legionella; (9) Pseudomonas aeruginosa and other
Gram-negative opportunists and; (10) Mycobacterium tuberculosis
and atypical Mycobacteria. Tulane University Health Sciences Center,
New Orleans, LA. 1999-2003 Co-course director of Graduate course: “Genetics and Physiology of Bacterial Pathogens” (MIIM 704). Includes development of lecture handouts and intramural course materials. 13 lectures. Lecture topics include: (1) Recombinant DNA and genomics; (2) Transduction; (3) Recombination; (4) Bioenergetics; (5) Regulation of metabolic pathways; (6) Gram negative cell wall synthesis; (7) Protein export and secretion; (8) Chemotaxis; (9) Adhesins; (10) Intracellular lifestyles of bacterial pathogens; (11) Capsules; (12) Inorganic metabolism and; (13) Regulation of virulence factors: two-component transcriptional regulators. Tulane University Health Sciences Center, New Orleans, LA. 2001-present Graduate course: Advanced Immunology: 1 lecture on Lung immunology. Tulane University Health Sciences Center, New Orleans, LA. 1999-present Molecular and Cellular Biology Program. Introduction to research topics. Tulane University Health Sciences Center, New Orleans, LA. 2000 Graduate course: Biochemistry 718: 2 lectures on recombination. Tulane University Health Sciences Center, New Orleans, LA. 2000 Graduate course: Human Genetics: 2 lectures on transformation, conjugation, transduction and transposition. Tulane University Health Sciences Center, New Orleans, LA. 1999-2000 Course Director for Medical Microbiology. Tulane University Health Sciences Center, New Orleans, LA.
1999 Instructor and co-course director of graduate course, “Genetics, Physiology, and Molecular Aspects of Microbial Pathogenesis” 10 lectures. Lecture topics included: (1) Composition, structure and function of bacterial cells; (2) Assembly and polymerization: the bacterial interior and the bacterial envelope; (3) chemotaxis; (4) bacterial growth; (5) Coordination of metabolism: temperature, pH and pressure; (6) Bacterial genome and plasticity; (7) Genetic exchange, recombination; (8) Transcriptional regulation; (9) Pseudomonas aeruginosa and; (10) Tuberculosis 1998 Four lectures in Medical Microbiology 500. University of Michigan Medical School, Ann Arbor, Michigan. 1997 Small group leader in Infectious Disease Sequence. University of Michigan Medical School, Ann Arbor, Michigan. 1994-1995 Microbial pathogenesis lecture. University of Texas Health Science Center at San Antonio, Texas. 1990 Virology Laboratory. University of North Texas, Denton, Texas. 1990-1992 Zoology Laboratory. University of North Texas, Denton, Texas. 1989-1992 Molecular Biology Laboratory. University of North Texas, Denton, Texas. 1988-1989 Genetics Laboratory. University of North Texas, Denton, Texas. 1987-1988 Cell Biology Laboratory. University of North Texas, Denton, Texas. 1986-1987 General Microbiology Laboratory. University of North Texas, Denton, Texas. Invited Lectureships and Symposia: 2005 University of Oklahoma Health Sciences Center, Oklahoma City, OK. “AlgR: A Pseudomonas aeruginosa Global Transcriptional Regulator of Virulence.” Invited Speaker. January 31st. 2004 Cystic Fibrosis Foundation Williamsburg Annual Meeting, Williamsburg, VA. “What Does AlgR Control Besides Alginate and Twitching Motility” Invited Speaker. June 4-6. 2004 Tulane University Health Sciences Center, Pulmonary Medicine, “The Pseudomonas aeruginosa Transcriptional Regulator AlgR controls Cyanide as well as Alginate Production in Clinical CF Isolates.” Invited Speaker. December 10. 2004 Louisiana State University Health Sciences Center (LSUHSC), Pulmonary Medicine Department. New Orleans, LA. Invited speaker. 2004 LSUHSC, Department of Medicine, Program in Gene Therapy. New Orleans, LA. Invited speaker. March 29. The Pseudomonas aeruginosa transcriptional regulator AlgR controls more than alginate in Cystic Fibrosis Isolates. 2003 Loyola University Undergraduate Seminar series, Invited speaker. 2003 ASM Conference on Microbial Biofilms, British Columbia, Canada, Invited speaker 2003 North American Cystic Fibrosis Conference, Anaheim CA. Invited speaker. 2003 Medical College of Wisconsin, Milwaukee, Wisconsin. Invited speaker. 2003 University of North Texas, Denton, Texas. Invited speaker 2003 Tulane University Health Sciences Center (TUHSC), Department of Medicine, New Orleans, LA. Invited speaker 2003 LSUHSC, Department of Genetics, New Orleans, LA. Invited speaker. 2002 LSUHSC, Pulmonary Medicine Department. New Orleans, LA. Invited speaker. 2000 LSUHSC, Department of Microbiology and Immunology. New Orleans, LA. Invited speaker. 2000 TUHSC, Department of Pediatrics, New Orleans, LA. Invited speaker. 2000 TUHSC, Department of Pathology, New Orleans, LA. Invited Speaker. 1999 TUHSC, Department of Biochemistry, New Orleans, LA. Invited Speaker. 1999 TUHSC, Department of Pharmacology, New Orleans, LA. Invited Speaker. 1999 TUHSC, Infectious Disease AIDS series, New Orleans, LA. Invited Speaker. 1998 LSUHSC, Department of Pulmonary Medicine, New Orleans, LA. Invited speaker 1996 Conference on Microbial Biofilms, Snowbird, UT 1994 International workshop on Osmoadaptation. Osnabruck, Germany Honors, Awards and Fellowships: 2005 Tulane University Health Sciences Research Recognition Award 1996-1998 Cystic Fibrosis Foundation New Investigator Award 1993-1996 Cystic Fibrosis Foundation Postdoctoral Fellowship 1994 Genentech Inc. Cystic Fibrosis Foundation Postdoctoral Fellow Award 1993 NIH National Research Service Award (declined) 1981-1983 Tri-Beta Biological Honor Society 1983 American Heart Association grant for undergraduate research Professional Societies: 1987-present American Society for Microbiology Public Service: 2000 Habitat for Humanity National and International Committees, Official Appointments and Directorships: 2000 National Research Council of Ireland. Grant reviewer.
2004 Ad hoc Reviewer for NIH Special Emphasis Panel ZAI1-GLM-M Innate Immunity Program Project Review
2004 Ad hoc Reviewer for U.S. Civilian Research and Development Foundation Cooperative Grants Program
2004 Ad Hoc Reviewer for NIH Lung Cellular, Molecular, and Immunobiology Study Section.
2004 Ad Hoc Reviewer for Netherlands Grant
2005 Editorial Board of the journal Infection and Immunity
2005 Ad Hoc Reviewer for NIH Special Emphasis Panel ZDK1 GRB-6 (M1) NIDDK Cystic Fibrosis Research and Translational Core
2005 Ad Hoc Reviewer for Science Foundation of Ireland Committees (Intramural): 2005-present Departmental Promotion and Tenure Committee
2003-present Institutional Biosafety Committee
1999-present Graduate Advisory Committee 1999-present MCB Steering Committee 1999-present Department of Microbiology and Immunology graduate student search committee 1999-2000 Department of Microbiology and Immunology Faculty Search committee
1999-2000 Curriculum Committee 1999-2000 T2 Curriculum Committee Dissertation/Thesis Committees: Microbiology and Immunology-Tulane University Health Sciences Center Stephen E. Lizewski, Ph.D. (2003) (Committee Chairman) Alexander J. Carterson, Ph.D. (2005) (Committee Chairman) William Cody (Committee Chairman) Clint Coleman Post-doctoral students Anders Frisk, Ph.D. (2001-present) Debra W. Jackson, Ph.D. (2003) Lisa Morici, Ph.D. (2004-present) Undergraduate Summer Mentorship Programs: Louisiana Alliance Minority Program (L.A.M.P.) 2001 Brian Ashford 2003 Kendra Simpson Summer Pipeline Research Initiative: the Tulane Experience (S.P.R.I.T.E.) 2001 William Cody 2003 Ryan Jupiter 2004 Cherie Cross (M.A.R.C.) 1999 Ramona Ussin 2000 LaQuita Rogers Publications in Referred Journals: 1. Upadhyay, J., Schurr, M. J. and R. J. Lesseps. Phase contrast and scanning electron microscopy of a soil amoeba Hartmanella glebae. Proceedings of the 44th Annual Meeting of electron microscopy society of America. 300-301. 1986. 2. Zimmerman, E. G., Akins, D. R., Planz, J. V. and M. J. Schurr. A rapid procedure or isolating mitochondrial DNA. Gene. Analys. Techn. 5:102-104. 1988. 3. Schurr, M. J., Martin, D. W., Mudd, M. H., Hibler, N. S., Boucher, J. C. and V. Deretic. The algD promoter: regulation of alginate production by Pseudomonas aeruginosa. Cell. Mol. Biol. Res. 39:371-376. 1993. 4. Martin, D. W., Schurr, M. J., Mudd, M. H. and V. Deretic. Differentiation of Pseudomonas aeruginosa into the alginate-producing form: Inactivation of mucB causes conversion to mucoidy. Mol. Microbiol. 9:497-506. 1993. 5. Martin, D. W., Schurr, M. J., Mudd, M. H., Govan, J. R. W., Holloway, B. W. and V. Deretic. Mechanism of conversion to mucoidy in Pseudomonas aeruginosa Infecting cystic fibrosis patients. Proc. Natl. Acad. Sci. USA. 90:8377-8381. 1993. 6. Deretic, V., Martin, D. W., Schurr, M. J., Mudd, M. H., Hibler, N. S., Curcic, R. and J. C. Boucher. Conversion to mucoidyin Pseudomonas aeruginosa. Bio/Technology. 11:1133-1136. 1993. 7. Schurr, M. J., Martin, D. W., Mudd, M. H. and V. Deretic. Gene cluster controlling conversion to alginate overproducing phenotype in Pseudomonas aeruginosa: functional analysis in a heterologous host and role in the instability of mucoidy. J. Bacteriol. 176:3375-3382. 1994. 8. Deretic, V., Schurr, M. J., Boucher J. C. and D. W. Martin. Conversion of Pseudomonas aeruginosa to mucoidy in cystic fibrosis: Environmental Stress and regulation of bacterial virulence by alternative sigma factors. J. Bacteriol. 176:2773-2780. 1994. 9. Martin, D. W., Schurr, M. J., Yu, H. and V. Deretic. Analysis of promoters controlled by the putative sigma factor AlgU regulating conversion to mucoidy in Pseudomonas aeruginosa: Relationship to sE and stress response. J. Bacteriol. 176:6688-6696. 1994. 10. Schurr, M. J., Vickrey, J. F., Kumar, A. P., Campbell, A. L., Cunin, R., Benjamin, R. C., Shanley, M. S. and G. A. O’Donovan. Aspartate transcarbamoylase genes of Pseudomonas putida: Requirement for an inactive dihydroorotase for assembly into the dodecameric holoenzyme. J. Bacteriol. 177:3259-3268. 1995. 11. Yu, H., Schurr, M. J. and V. Deretic. Functional equivalence of Escherichia coli sE and Pseudomonas aeruginosa AlgU: E. coli rpoE restores mucoidy and reduces sensitivity to reactive oxygen intermediates in algU mutants with P. aeruginosa. J. Bacteriol. 177:3259-3268. 1995. 12. Schurr, M. J., Yu, H., Boucher, J. C., Hibler, N. S. and V. Deretic. Multiple promoters and induction by heat shock of the gene encoding the alternative sigma factor AlgU (sE) which controls mucoidy in cystic fibrosis isolates of Pseudomonas aeruginosa. J. Bacteriol. 177:5670-5679. 1995. 13. Deretic, V., Schurr, M. J. and H. Yu. P. aeruginosa, mucoidy and the chronic infection phenotype in cystic fibrosis. Trend. Microbiol. 3:351-356. 1995. 14. Schurr, M. J., Yu, H., Martinez-Salazar, J. M., Hibler, N. S. and V. Deretic. Biochemical characterization and posttranslational modification of AlgU, a regulator of stress response in Pseudomonas aeruginosa. Biochem. Biophys. Res. Comm. 216:874-880. 1995. 15. Schurr, M. J., Yu, H., Martinez-Salazar, J. M., Boucher J. C. and V. Deretic. Control of AlgU, member of the sE-like family of stress sigma factors, by the negative regulators MucA and MucB and P. aeruginosa conversion to mucoidy in cystic fibrosis. J. Bacteriol. 178:4997-5004. 1996. 16. Yu, H., Schurr, M. J., Boucher, J. C., Martinez-Salazar, J. M., Martin, D. W. and V. Deretic. Molecular mechanism of conversion to mucoidy in Pseudomonas aeruginosa, p. 384-397. In Pseudomonas: S. Silver, T. Nakazowa, D. Haas (eds.). ASM Press, Washington D.C. 1996. 17. Boucher, J. C., Martinez-Salazar, J. M., Schurr, M. J., Mudd, M. H., Yu, H. and V. Deretic. Two distinct loci affecting conversion to mucoidy in P. aeruginosa in cystic fibrosis encode homologs of the serine protease HtrA. J. Bacteriol. 178:511-523. 1996. 18. Yu, H., Mudd, M. H., Boucher, J. C., Schurr, M. J. and V. Deretic. Identification of the algZ Gene Upstream of the Response Regulator algR and Its Participation in the Control of Alginate Production in Pseudomonas aeruginosa. J. Bacteriol. 179:187-193. 1996. 19. Schurr, M. J. and V. Deretic. Coordinate Regulation of Heat Shock Response and Conversion to Mucoidy in Pseudomonas aeruginosa: Implications for Pathogenesis in Cystic Fibrosis. Mol. Microbiol. 24:411-420. 1997. 20. Boucher, J. C., Schurr, M. J., Yu, H., Rowen, D. W. and V. Deretic. Pseudomonas aeruginosa in cystic fibrosis: role of mucC in the regulation of alginate production and stress sensitivity. Microbiology. 143: 3473-3480. 1997. 21. Boucher, J. C., Schurr, M. J. and V. Deretic. Dual Regulation of mucoidy in Pseudomonas aeruginosa and sigma factor antagonism. Mol. Microbiol. 36:341-351. 2000. 22. Wilson, J., Schurr, M. J., LeBlanc, C., Ramamurthy, R., Buchanan, K. and C. A. Nickerson. Mechanisms of Microbial Pathogenicity. (Invited Review). British Medical Journal Publishing Group – Postgrad. Med. J. 78:216-224. 2002. 23. Lizewski, S. E., Lundberg, D. S. and M.J. Schurr. The transcriptional regulator AlgR is essential for Pseudomonas aeruginosa pathogenesis. Infect. Immun. 70:6083-6093. 2002. 24. Dang, Y. N. T., Rao, A., Kastl, P. R., Blake, R. C., Schurr, M. J. and D. A. Blake. Quantifying Pseudomonas aeruginosa adhesion to contact lenses. Eye and Contact lens 29:65-68. 2003. 25. Lizewski, S. E., Schurr, J. R., Jackson, D. W., Frisk, A., Carterson, A. J. and M. J. Schurr. Identification of AlgR Regulated Genes in Pseudomonas aeruginosa Using Microarray Analysis. J. Bacteriol. 186:5672-5684. 2004. 26. Frisk, A., Schurr, J. R., Wang, G., Bertucci, D., Marrero, L., Hwang, S. H., Hassett, D. J. and M. J. Schurr. Transcriptome analysis of Pseudomonas aeruginosa after interaction with human airway epithelial cells. Infect. Immun. 72:5433-5438. 2004. 27. Carterson, A. J., Morici, L. A., Jackson, D. W., Frisk, A., Lizewski, S. E., Jupiter, R., Simpson, K., Kunz, D. A., Davis, S.H., Schurr, J. R., Hassett, D. J. and M. J. Schurr. The Transcriptional Regulator AlgR Controls Cyanide Production in Pseudomonas aeruginosa J. Bacteriol. 186:6837-6844. 2004. 28. Hassett, D. J., Lymar, S. V., Rowe, J. J., Schurr, M. J., Passador, L., Herr, A. B., Yoon, S. S., Lau, G. W., Winsor, G. L. and F. S. L. Brinkman. Anaerobic metabolism by Pseudomonas aeruginosa in cystic fibrosis airway biofilms: Role of nitric oxide, quorum sensing and alginate production. In: Strict and Facultative Anaerobes:Medical and Environmental Aspects. Editors: P. Zuber and M. Nakano. CRC Press, Boca Raton, FL. 87-109. 2004. 29. Carterson, A. J., Ott, C. M., Clarke, M. S., Pierson D. L., Vanderburg, C. R., Nickerson, C. A., Buchanan, K. L. and M. J. Schurr. A549 Lung Epithelial Cells Grown As 3-D Aggregates: Alternative Tissue Culture Model for P. aeruginosa Pathogenesis. Infect. Immun. 73:1129-1140. 2005. 30. Steele, C., Schurr, M. J. and J. K. Kolls. Exacerbated inflammatory response in the lungs of gd T cell-deficient mice after Pseudomonas aeruginosa challenge. Infection and Immunity. Manuscript in preparation.
31. Yoon, S. S., Hennigan, R. F.,
Herr, A. B., Groce, S. L., Munck, E., Lipscomb, J. D., Kiley, P. J.,
Hwang, S. H., Schurr, M. J. and D. J. Hassett. Pseudomonas
aeruginosa lacking nitric oxide reductase is protected during
anaerobic growth by nitric oxide-mediated inactivation of ANR and two
oxygen-dependent enzymes. Manuscript in preparation. |